Prolyl‐isomerase Pin1 controls normal and cancer stem cells of the breast
نویسندگان
چکیده
منابع مشابه
Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast
Mammary epithelial stem cells are fundamental to maintain tissue integrity. Cancer stem cells (CSCs) are implicated in both treatment resistance and disease relapse, and the molecular bases of their malignant properties are still poorly understood. Here we show that both normal stem cells and CSCs of the breast are controlled by the prolyl-isomerase Pin1. Mechanistically, following interaction ...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2013
ISSN: 1757-4676,1757-4684
DOI: 10.1002/emmm.201302909